Wherever You Are sold nearly 250,000 copies in two days - more than X Factor winners Little Mix sold in their entire first week.
The early sales figures almost guarantee them the coveted Christmas number one slot this Sunday.
Bookmakers Ladbrokes and William Hill have both suspended betting on the Military Wives taking the top spot claiming it is a "done deal".
On Tuesday morning, the wives gave their bid for the top spot a further push by performing for Christmas shoppers on London's Oxford Street.Chris Evans has been a big supporter of the Military Wives' single
They were put together by choirmaster Gareth Malone for the BBC2 show The Choir which climaxed with the group performing at the Festival of Remembrance at the Royal Albert Hall.
Jo Millthorpe and Sarah Clarke from the group told Sky News it snowballed into something spectacular:
"This time a few months ago, we couldn't have imagined. We set out to have a giggle and a get together.
"We honestly thought the Royal Albert Hall would be the end but we couldn't be more wrong. It just keeps getting better."
Jo added: "We've put the shoe on the other foot really. We're all so proud of our men - and now they've got something to be proud of us for."Simon Cowell has conceded The Military Wives will beat the X Factor winners
Malone says the song has struck a chord with the public, as they reflect on conflicts past and present.
"This single comes at a time when we're thinking about Afghanistan and realising the sacrifices made - not just the fatalities - but the small sacrifices made by their partners on a daily basis," he said.
The track has been championed by Radio 2's Chris Evans.
X Factor supremo Simon Cowell has already conceded that the Wives will beat Little Mix to the top of the festive chart when it is announced on Christmas Day.
After the X Factor winners went to number one on Sunday, he tweeted: "Congrats to Little Mix & congrats to Military Wives. It's a great cause & a worthy Christmas No.1".
Bookmaker William Hill is resigned to losing a five figure sum as they watch the women storm the charts.
Rupert Adams, from the company, says bets are all but off.
"We are so amazed by them that we are offering just 3/1 that the single sells a million copies by Christmas Day."