The two acts came joint top in a survey carried out by industry body PRS for Music to find which acts have headlined the most major venues in 2011 - playing 29 each.
Murs said it was "a real honour" to win the award, adding: "The last two years have been incredible for me - I've achieved so much and it's great to be recognised for all the work I've put in. Thanks to everyone who's come to see me play live - there's lots more to come."
A statement released by JLS said: "This is a great achievement and really goes to show how hard we have been working this year."
The two acts pipped reformed man-band Take That to the top of the chart.
The five-piece, reunited with Robbie Williams, played to around 1.75 million people during their sell-out tour of the UK and Ireland that saw them play 28 major venues.
Other acts in the top 10 included Westlife and former Oasis frontman Liam Gallagher's new band Beady Eye.
Barney Hooper from PRS for Music said: "Performing live and going on tour are fundamental to any artist and is a great way for them to engage with their fans. Congratulations to both JLS and Olly Murs and all the songwriters who they have worked with to create the music that so many people are enjoying."